Effects of Blast-induced Neurotrauma on Pressurized Rodent Middle Cerebral Arteries
نویسندگان
چکیده
منابع مشابه
Blast-induced neurotrauma in whales.
A majority of investigations on primary blast injuries have focused on gas-containing organs, while the likelihood of blast-induced neurotrauma remains underrated. In Norway minke whales (Balaenoptera acutorostrata) are hunted using small fishing boats rigged with harpoon guns, which fire harpoons tipped with a grenade containing a charge of 30-g penthrite. The grenade detonates 60-70 cm inside...
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Although advances are being made in identifying some of the essential mechanisms that may lead to chronic neurological deficits after blast-exposure(s), clinical needs continue to exceed current knowledge. In their current article, Brenner and colleagues address the importance of basic science in guiding new diagnostic and treatment strategies. Together with Wilkinson et al., they emphasize one...
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The high incidence of blast exposure on today’s battlefield has been strongly associated with traumatic brain injuries. Anecdotal evidence of prolonged apnea following blast exposure has been observed in military personnel and is commonly reproduced in animal neurotrauma models. Animal models have shown that apnea tolerance is both dose and species-dependent; important factors include primary b...
متن کاملProtective effects of decay-accelerating factor on blast-induced neurotrauma in rats
BACKGROUND Blast-induced neurotrauma (BINT) is the signature life threatening injury of current military casualties. Neuroinflammation is a key pathological occurrence of secondary injury contributing to brain damage after blast injury. We have recently demonstrated that blast-triggered complement activation and cytokine release are associated with BINT. Here, we evaluated if administration of ...
متن کاملExplosive blast neurotrauma.
Explosive blast traumatic brain injury (TBI) is one of the more serious wounds suffered by United States service members injured in the current conflicts in Iraq and Afghanistan. Some military medical treatments for blast TBI that have been introduced successfully in the war theater include decompressive craniectomy, cerebral angiography, transcranial Doppler, hypertonic resuscitation fluids, a...
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ژورنال
عنوان ژورنال: Journal of Visualized Experiments
سال: 2019
ISSN: 1940-087X
DOI: 10.3791/58792